生长抑素受体2重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
生长抑素受体2重组兔单抗
货号:bsm-61177R
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概述

产品编号
bsm-61177R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
Somatostatin Receptor 2 Recombinant Rabbit mAb
中文名称
生长抑素受体2重组兔单抗
英文别名
SST2; SRIF-1; SS2R; SSTR-2; Smstr-2; Smstr2; SSR2_HUMAN; SSTR2; SS-2-R; SS2-R; SSR2_MOUSE; SSR2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human SSTR2: 311-369
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
8H1
理论分子量
41
检测分子量
41
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
SSTR2的表达在肿瘤的分布、发生和发展中起重要作用。目前主要用于肿瘤方面的研究。
背景资料
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.
生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗生长抑素受体2重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHumanMouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:50-200
IHC-FHuman, Mouse, Rat1:50-200
IFHuman, Mouse, Rat1:50-200
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
SSTR2
蛋白名
Somatostatin receptor type 2
亚基
The C-terminus interacts with SHANK1 PDZ domain.
亚细胞定位
Cell membrane; Multi-pass membrane protein.
组织特异性
Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

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