CD97 Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,ICC/IF,IP | Bioss

bsm-61103R

重组兔单抗

CD97 Recombinant Rabbit mAb

CD97重组兔单抗

CD97; TM7LN1; AGRE5_HUMAN; ADGRE5; Leukocyte antigen CD97; AGRE5_MOUSE; adhesion G protein-coupled receptor E5; CD97 antigen; CD97 molecule; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; seven transmembrane helix receptor

Rabbit

A synthesized peptide derived from human ADGRE5: 450-500

IgG

Liquid

affinity purified by Protein A

Recombinant

7E8

92 kDa

92 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.

ADGRE5

Adhesion G protein-coupled receptor E5

Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) interacts with chondroitin sulfate.

Cell membrane; Multi-pass membrane protein.
CD97 antigen subunit alpha: Secreted, extracellular space.

Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid.

Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 5 EGF-like domains.
Contains 1 GPS domain.

Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.