EP4 Rabbit pAb (一抗) | Bioss
货号：bs-24918R
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概述
产品编号
bs-24918R
英文名称
EP4 Rabbit pAb
中文名称
前列腺素E受体蛋白4抗体
英文别名
EP4; EP4R; Ptgerep4; Ptger; PGE2R-EP4; PE2R4_HUMAN; PTGER4; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER2; PE2R4_MOUSE; PE2R4_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse EP4 : 1-100/513 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
53 kDa
检测分子量
55 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse | 1:500-2000 | |
| Flow-Cyt | Mouse | 2ug/Test |
交叉反应
交叉反应: Mouse
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靶标
基因名
PTGER4
蛋白名
Prostaglandin E2 receptor EP4 subtype
亚基
Interacts with FEM1A.
亚细胞定位
Cell membrane.
组织特异性
High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
翻译后修饰
Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
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