NFKB p65 Knockout Hela Cell Line (Pool) (KO细胞系) | Bioss
货号：K025-1-1P
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概述
产品编号
K025-1-1P
产品类型
KO/KD细胞系
英文名称
NFKB p65 Knockout Hela Cell Line (Pool)
中文名称
NFKB p65基因敲除Hela细胞（Pool）
英文别名
NF kB P65; NF-kB p65; NFKBp65; NF-κBp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription Factor p65.
SWISS
Gene ID
gRNA种属
Human
细胞名称
Hela
培养体系
90％DMEM + 10％FBS + 1％P/S
冻存液体系
90％FBS + 10％DMSO
敲除区域
E3
鉴定方法
PCR + Sanger Sequencing
突变描述
Knockout achieved by using CRISPR/Cas9, Deletion of the selection cassette in exon 3.
细胞数目
1-5×10⁶
产品组成
1 vial knockout cell line and 1 vial parental cell line.
运输条件
Dry Ice
保存条件
Stored in liquid nitrogen for a long time.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
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靶标
基因名
RELA
蛋白名
Transcription factor p65