自噬蛋白5重组兔单抗

bsm-52596R

重组兔单抗

ATG5 Recombinant Rabbit mAb

自噬蛋白5重组兔单抗

APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5; 2010107M05Rik; 3110067M24Rik; Atg5l; Paddy; ATG5_HUMAN; ATG5; Apoptosis-specific protein; ATG5_MOUSE; ATG5_RAT;

Rabbit

A synthesized peptide derived from human ATG5: 1-64

IgG

Liquid

affinity purified by Protein A

Recombinant

4G5

32 kDa

1mg/ml

0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

In yeast, autophagy is an essential process for survival during nutrient starvation and cell differentiation. The process of autophagy is characterized as a non-selective degradation of cytoplasmic proteins into membrane stuctures called autophagosomes, and it is dependent on several proteins, including the autophagy proteins APG5 and APG7. Yeast Apg7 and the human homolog, APG7, share similarities with the ubiquitin-activating enzyme E1 in Saccharomyces cerevisiae and are likewise responsible for enzymatically activating the autophagy conjugation system. Apg5 and the human homolog, APG5 (also designated apoptosis-specific protein or APS), function as substrates for the autophagy protein Apg12. These proteins are covalently bonded together to form Apg12/APG5 conjugates, which are required for the progression of autophagy.