水通道蛋白4重组兔单抗

bsm-61035R

重组兔单抗、mIHC精品抗体

AQP4 Recombinant Rabbit mAb

水通道蛋白4重组兔单抗

AQP-4; MIWC; WCH4; MLC4; hAQP4; AQP4_BOVIN; AQP4; Mercurial-insensitive water channel (MIWC); AQP4_HUMAN; AQP4_MOUSE; AQP4_RAT;

Rabbit

A synthesized peptide derived from human Aquaporin 4: 300-323

IgG

Liquid

affinity purified by Protein A

Recombinant

9F10

36

0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

通道蛋白（Channel Protein）
水通道蛋白(AQPs)广泛分布于机体不同组织器官中,脑组织中的水通道蛋白主要为AQP4.
AQP-4蛋白主要在星型胶质细胞和室管膜细胞内表达,尤其在于毛细血管和软脑膜直接接触的胶质细胞上及血管周表达丰富.
水通道蛋白4的分布特点与其功能密切相关,可能是脑脊液重吸收、渗透压调节、脑水肿形成等生理、病理过程的分子生物学基础.研究水通道蛋白4可为脑水肿及水代谢疾病提供分子水平的理论依据,同时为临床治疗脑水肿及水代谢疾病提供一种新途径.

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]