G1氨基丁酸A型受体相似蛋白2重组兔单抗

bsm-61002R

重组兔单抗

GABARAPL2 Recombinant Rabbit mAb

G1氨基丁酸A型受体相似蛋白2重组兔单抗

ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2; 0610012F20Rik; 2900019O08Rik; AABR07071000.1; GBRL2_HUMAN; GABARAPL2; GABA(A) receptor-associated protein-like 2; Ganglioside expression factor 2 (GEF-2); General protein transport factor p16; Golgi-associated ATPase enhancer of 16 kDa (GATE-16); MAP1 light chain 3-related protein; FLC3A; GBRL2_MOUSE; GBRL2_RAT;

Rabbit

A synthesized peptide derived from human GABARAPL2: 70-117

IgG

Liquid

affinity purified by Protein A

Recombinant

14D2

14 kDa

1m/ml

0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GABAA受体相关蛋白相似蛋白2；GABA受体A型相关蛋白样2

In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing (1). GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2,3). In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein) (4-6). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton (6). The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex (6).