FDFT1 Rabbit pAb (一抗) | Bioss

bs-11517R

宠物抗体

FDFT1 Rabbit pAb

法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体

DGPT; ERG9; SQS; SQSD; SS; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1; 2.5.1.21; FDFT_MOUSE;

Rabbit

KLH conjugated synthetic peptide derived from human FDFT1: 321-417/417

IgG

Liquid

affinity purified by Protein A

Polyclonal

48 kDa

50 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.