Myeloperoxidase Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF | Bioss

bsm-55545R

重组兔单抗

Myeloperoxidase Recombinant Rabbit mAb

髓过氧化物酶重组兔单抗

mKIAA4033; PERM_HUMAN; MPO; 1.11.2.2; PERM_MOUSE; myeloperoxidase

Rabbit

KLH conjugated synthetic peptide derived from Mouse MPO

IgG

Liquid

Affinity Purification

Recombinant

SB135

PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol.

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

髓过氧化物酶（MPO）是一种过氧化物酶，由17号染色体上的MPO基因编码。MPO在中性粒细胞中表达得最多，并产生次氯酸以进行抗菌活动，其钠盐是漂白剂中的化学物质。它是一种溶酶体蛋白，储存在中性粒细胞的嗜氮颗粒中，并在脱颗粒时释放到细胞外空间。MPO在急性骨髓性白血病、粒细胞性白血病、单核细胞性白血病、成髓细胞瘤和其它造血系统疾病的成髓细胞和未成熟骨髓细胞中表达，在某些肺癌和卵巢癌也可见表达。

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.

MPO

Myeloperoxidase

Tetramer of two light chains and two heavy chains.

Lysosome.

Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.

Belongs to the peroxidase family. XPO subfamily.

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.