CROT Rabbit pAb (一抗) | Bioss
货号：bs-5048R
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概述
产品编号
bs-5048R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
CROT Rabbit pAb
中文名称
肉碱氧位甲基转移酶抗体
英文别名
COT; 1200003H03Rik; OCTC_HUMAN; CROT; 2.3.1.137; OCTC_MOUSE;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CROT: 41-140/612
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
70 kDa
检测分子量
70 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism
Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation
Signal Transduction > Metabolism > Lipid metabolism
Tags & Cell Markers > Subcellular Markers > Organelles > Peroxisome
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
CROT (Carnitine O-octanoyltransferase) is involved in the beta-oxidation of fatty acids. It catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. It has highest activity towards the C6 to C10 chain length substrate. It is a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Rabbit, Dog, Horse | 1:500-2000 |
| IHC-P | Rat | Human, Mouse, Rabbit, Dog, Horse | 1:100-500 |
| IHC-F | Rat | Human, Mouse, Rabbit, Dog, Horse | 1:100-500 |
| IF | Rat | Human, Mouse, Rabbit, Dog, Horse | 1:100-500 |
交叉反应
交叉反应: Human, Rat (predicted: Mouse, Rabbit, Dog, Horse)
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靶标
基因名
CROT
蛋白名
Peroxisomal carnitine O-octanoyltransferase
亚基
Monomer (Probable).
亚细胞定位
Peroxisome.
相似性
Belongs to the carnitine/choline acetyltransferase family.
功能
Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
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