E-Selectin Mouse mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
E-Selectin Mouse mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss
货号:bsm-43646M
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概述

产品编号
bsm-43646M
英文名称
E-Selectin Mouse mAb
中文名称
E选择素单克隆抗体
英文别名
CD62E; ELAM; ELAM1; ESEL; LECAM2; selectin-e; E-selectin; ELAM-1; LYAM2_HUMAN; SELE; CD62 antigen-like family member E; Endothelial leukocyte adhesion molecule 1 (ELAM-1); Leukocyte-endothelial cell adhesion molecule 2 (LECAM2); LYAM2_MOUSE; LYAM2_RAT;
抗体来源
Mouse
免疫原
Recombinant human E-Selectin protein
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Monoclonal
克隆号
1G1
理论分子量
65 kDa
检测分子量
61 kDa
储存液
0.01M PBS(pH7.4).
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
E选择素(CD62E)是活化的内皮细胞表面表达的黏附分子,是白细胞与内皮细胞形成接触时的启动因子。E选择素是表达在血管内皮细胞表面的黏附分子。
背景资料
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
E选择素单克隆抗体-bsm-43646ME选择素单克隆抗体-bsm-43646ME选择素单克隆抗体-bsm-43646M

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman1:500-2000
IHC-PHuman1:100-500
IHC-FHuman1:100-500
IFHuman1:100-500

交叉反应

交叉反应: Human

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靶标

基因名
SELE
蛋白名
E-selectin
亚基
Interacts with PSGL1/SELPLG through the sialyl Lewis X epitope. PSGL1 sulfation appears not to be required for this interaction.
亚细胞定位
Membrane; Single-pass type I membrane protein.
相似性
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.
功能
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.

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