phospho-Glycogen synthase 1 (Ser641) Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,IP | Bioss

bsm-52159R

磷酸化抗体、重组兔单抗

phospho-Glycogen synthase 1 (Ser641) Recombinant Rabbit mAb

磷酸化葡萄糖合成酶1重组兔单抗

GSY; GYS; Gys3; MGS; GYS1_HUMAN; GYS1; Glycogen synthase 1; 2.4.1.11; Q8VEB0_MOUSE; GYS1_MOUSE; GYS1_RAT; glycogen synthase 1 (muscle); GYS1 (phospho-S641); p-GYS1; phospho-GYS1; GYS1 (phospho-Ser641)

Rabbit

KLH conjugated Synthesised phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser641: PA(p-S)VP

IgG

Liquid

affinity purified by Protein A

Recombinant

10C1

85 kDa

80 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.