MGLUR5 Rabbit pAb (一抗) | Bioss

bs-18801R

农牧业/家禽抗体

MGLUR5 Rabbit pAb

代谢型谷氨酸受体5B抗体

GPRC1E; MGLUR5; PPP1R86; mGlu5; 6430542K11Rik; Glu5R; mGluR5b; GRM5_HUMAN; GRM5; GRM5_MOUSE; GRM5_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human MGLUR5: 431-530/1212 <Extracellular>

IgG

Liquid

affinity purified by Protein A

Polyclonal

130 kDa

160 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.