SLC40A1 Rabbit pAb (一抗) | Bioss
货号：bs-3579R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bs-3579R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
SLC40A1 Rabbit pAb
中文名称
细胞膜铁转运蛋白FP1抗体
英文别名
FPN; FPN1; HFE4; IREG1; MST079; MSTP079; MTP1; SLC11A3; Dusg; MTP; Ol5; Pcm; Slc39a1; S40A1_HUMAN; SLC40A1; Ferroportin-1; Iron-regulated transporter 1; Solute carrier family 40 member 1; S40A1_MOUSE; Metal transporter protein 1 (MTP1); S40A1_RAT; CAR1; Cell adhesion regulator; Fpt1;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human SLC40A1: 201-300/571
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
63 kDa
检测分子量
63 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse | Human, Rat, Rabbit, Pig, Cow, Dog | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Cow, Dog)
相关产品
暂无相关产品
靶标
基因名
SLC40A1
蛋白名
Solute carrier family 40 member 1
亚基
Belongs to the S1LC40A transporter family.
亚细胞定位
Cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of polarized epithelial cells.
组织特异性
Expressed in placenta, intestine, muscle and spleen.
疾病
Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation.
相似性
Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
功能
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
同靶标产品
相关文献
提示: 发表研究结果有使用 bs-3579R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。
具体参考文献:bs-3579R 被引用于7文献中