TPH Rabbit pAb (一抗) | Bioss

bs-1215R

宠物抗体、农牧业/家禽抗体

TPH Rabbit pAb

色氨酸羟化酶抗体

TPRH; TRPH; Tph; TPH1_HUMAN; TPH1; Tryptophan 5-monooxygenase 1; 1.14.16.4; TPH1_MOUSE; TPH1_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human TPH: 31-150/444

IgG

Liquid

affinity purified by Protein A

Polyclonal

49 kDa

49 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

色氨酸在脑中首先由色氨酸羟化酶(tryoptophan hydroxylase)催化生成5羟色氨酸(5hydroxytryptophan)，再经脱羧酶作用生成5羟色胺，色氨酸羟化酶（TPH）是5-HT生物合成的限速酶，因此，色氨酸羟化酶的缺少可导致5-羟色胺的含量下降。色氨酸羟化酶主要在肝脏内代谢。

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009].