CD30 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-54798R

重组兔单抗

CD30 Recombinant Rabbit mAb

CD30重组兔单抗

TNR8_HUMAN; TNFRSF8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; D1S166E; TNF receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8

Rabbit

A synthesized peptide derived from human CD30: 570-595/595

IgG

Liquid

affinity purified by Protein A

Recombinant

3A20

62 kDa

110 kDa

1mg/ml

0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD30是一种单链糖蛋白，标记活化T和B淋巴细胞，R-S细胞和部分淋巴滤泡间区免疫母细胞。CD30是霍奇金淋巴瘤的一个特异性标记，也是大细胞间变型淋巴瘤的诊断型标志。

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

TNFRSF8

Tumor necrosis factor receptor superfamily member 8

Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.

Isoform Long: Cell membrane; Single-pass type I membrane protein.
Isoform Short: Cytoplasm.

Detected in thymus and in activated splenocytes.

Phosphorylated on serine and tyrosine residues.

Contains 6 TNFR-Cys repeats

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.