AQP-CHIP; CHIP28; CO; AQP-1; CHIP29; AQP1_BOVIN; AQP1; Aquaporin-CHIP; Water channel protein CHIP29; AQP1_CANLF; AQP1_HUMAN; Channel-like integral membrane protein of 28 kDa; Urine water channel; AQP1_MOUSE; Delayed early response protein 2 (DER2); AQP1_RAT; AQP1_SHEEP;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Aquaporin 1: 214-269
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
2H11
理论分子量
28 kDa
浓度
1mg/ml
储存液
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Mouse, Rat
Human
1:1000-5000
IHC-P
Human, Mouse, Rat
1:200-1000
IHC-F
Human, Mouse, Rat
1:200-1000
IF
Human, Mouse, Rat
1:200-1000
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
AQP1
蛋白名
Aquaporin-1
亚基
Homotetramer. Interacts with EPHB2; involved in endolymphproduction in the inner ear (By similarity).
亚细胞定位
Membrane; Multi-pass membrane protein.
组织特异性
Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
相似性
Belongs to the MIP/aquaporin (TC 1.A.8) family.
功能
Forms a water-specific channel that provides the plasmamembranes of red cells and kidney proximal tubules with highpermeability to water, thereby permitting water to move in thedirection of an osmotic gradient.