Fatty Acid Synthase Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-54469R

重组兔单抗

Fatty Acid Synthase Recombinant Rabbit mAb

脂肪酸合成酶重组兔单抗

FAS; OA-519; SDR27X1; A630082H08Rik; FAS_CHICK; FASN; 2.3.1.85; FAS_BOVIN; FAS_HUMAN; Type I fatty acid synthase; FAS_MOUSE; FAS_RAT; Type I FAS; fatty acid synthase; short chain dehydrogenase/reductase family 27X, member 1; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-oxoacyl-[acyl-carrier-protein] synthase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Enoyl-[acyl-carrier-protein] reductase; Acyl-[acyl-carrier-protein] hydrolase

Rabbit

A synthesized peptide derived from human Fatty acid synthase: 2450-2511

IgG

Liquid

affinity purified by Protein A

Recombinant

9B6

273 kDa

290 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成与降解（Synthesis and Degradation） 脂肪酸合成酶fatty acid synthase是一种新的肿瘤标志物,高表达常提示肿瘤的预后不良.

FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation.

FASN

Fatty acid synthase

Homodimer which is arranged in a head to tail fashion.

Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Ubiquitous. Prominent expression in brain, lung, and liver.

Contains 1 acyl carrier domain.

Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.