活化转录因子4重组兔单抗

bsm-52667R

重组兔单抗

ATF4 Recombinant Rabbit mAb

活化转录因子4重组兔单抗

CREB-2; CREB2; TAXREB67; TXREB; Atf-4; C/ATF; ATF4_HUMAN; ATF4; cAMP-dependent transcription factor ATF-4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2 (CREB-2 | cAMP-responsive element-binding protein 2); Tax-responsive enhancer element-binding protein 67 (TaxREB67); Q96AQ3_HUMAN; ATF4_MOUSE; C/EBP-related ATF (C/ATF); Q5U4B2_MOUSE; Q8CF69_MOUSE; ATF4_RAT; Activating transcription factor 4 (rATF-4);

Rabbit

A synthesized peptide derived from human ATF4: 1-220/351

IgG

Liquid

affinity purified by Protein A

Recombinant

9C3

38 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.