精氨酸酶1重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
精氨酸酶1重组兔单抗
货号:bsm-56207R
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概述

产品编号
bsm-56207R
产品类型
重组兔单抗
英文名称
Arginase 1 Recombinant Rabbit mAb
中文名称
精氨酸酶1重组兔单抗
英文别名
AI; Arg-1; PGIF; ARGI1_BOVIN; ARG1; Liver-type arginase; Type I arginase; 3.5.3.1; ARGI1_HUMAN; ARGI1_MOUSE; ARGI1_PIG; ARGI1_RABIT; ARGI1_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Arginase 1: 11-71
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
19G6
理论分子量
35 kDa
浓度
1mg/ml
储存液
59% PBS, 40% Glycerol , 0.05% BSA(pH7.2), Preservative: 0.02% Proclin300.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
精氨酸酶1重组兔单抗精氨酸酶1重组兔单抗精氨酸酶1重组兔单抗精氨酸酶1重组兔单抗精氨酸酶1重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseRat1:500-2000
IHC-PMouse, Rat1:100-500
IHC-FMouse, Rat1:100-500
IFMouse, Rat1:100-500

交叉反应

交叉反应: Mouse, Rat

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靶标

基因名
ARG1
蛋白名
Arginase-1
亚基
Homotrimer.
亚细胞定位
Cytoplasm.
疾病
Defects in ARG1 are the cause of argininemia (ARGIN) ; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
相似性
Belongs to the arginase family.

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