lamin B1 Mouse mAb, Nuclear Loading Control (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-33040M

内参抗体、核蛋白内参抗体、mIHC精品抗体

lamin B1 Mouse mAb, Nuclear Loading Control

核纤层蛋白B（核内参）单克隆抗体

lamin-B1; ADLD; ADLDAT; LMN; LMN2; LMNB; MCPH26; LMNB1_CHICK; LMNB1; LMNB1_HUMAN; LMNB1_MOUSE; LMNB1_RAT;

Mouse

Recombinant human Lamin B Protein: 314-386/586

IgG1

Size : 50ul/100ul/500ul
Liquid

Size : 200ug (PBS only)
Lyophilized
Note: Centrifuge tubes before opening. Reconstitute the lyophilized product in distilled water. Optimal concentration should be determined by the end user.

affinity purified by Protein G

Monoclonal

9C11

64 kDa

64 kDa

1mg/ml

Size : 50ul/100ul/500ul
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Size : 200ug (PBS only)
0.01M PBS

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核膜标志物（Nuclear Envelope Marker） 核纤层蛋白(Lamin) 是紧贴核内膜的一层厚度为20～50nm的纤维蛋白层或纤维网络。核纤层与细胞质骨架、核骨架连成一个整体，一般认为核纤层将核被膜和染色质提供了结构支架。有学者研究认为：lamin蛋白与细胞凋亡及衰老有关联，它包括：核纤层蛋白A、核纤层蛋白B、核纤层蛋白C几个不同亚型的蛋白。

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010].