Integrin Alpha V Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,IP | Bioss

bs-1310R

Integrin Alpha V Rabbit pAb

整合素整合素αV（CD51）抗体

CD51; MSK8; VNRA; VTNR; ITAV_HUMAN; ITGAV; Vitronectin receptor; Vitronectin receptor subunit alpha;

Rabbit

KLH conjugated synthetic peptide derived from human Integrin Alpha V

IgG

Liquid

affinity purified by Protein A

Polyclonal

116 kDa

120-145 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.