Cytokeratin 20 Mouse mAb (一抗) - IHC-P,IHC-F,IF | Bioss

bsm-34154M

病理级抗体、mIHC精品抗体

Cytokeratin 20 Mouse mAb

细胞角蛋白20抗体

CD20; CK-20; CK20; K20; KRT21; 9030623C06Rik; K1C20_HUMAN; KRT20; Cytokeratin-20 (CK-20); Keratin-20 (K20); Protein IT; K1C20_MOUSE; K1C20_RAT; Cytokeratin-21 (CK-21);

Mouse

KLH conjugated synthetic peptide derived from human CK20

IgG2b,k

Liquid

affinity purified by Protein A

Monoclonal

18F9

48 kDa

1mg/ml

Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

结构蛋白（Structural Proteins）
CK-20细胞角蛋白-20主要用于肿瘤方面的研究，近年来大多用于消化系统恶性肿瘤的鉴别，主要在胞浆。

Cytokeratin 20 is a type I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Their genes are clustered in a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system and is present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack cytokeratin 20.