颗粒酶B重组兔单克隆抗体
Rrmab®兔单抗
货号：bsm-60779R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bsm-60779R
产品类型
重组兔单抗
英文名称
Granzyme B Recombinant Rabbit mAb
中文名称
颗粒酶B重组兔单克隆抗体
英文别名
C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT; CCP-1/C11; CCP1; Ctla-1; GZB; RNKP-1; GRAB_HUMAN; GZMB; Cathepsin G-like 1 (CTSGL1); Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease); Fragmentin-2; Granzyme-2; Human lymphocyte protein (HLP); T-cell serine protease 1-3E; 3.4.21.79; GRB; GRAB_MOUSE; Cytotoxic cell protease 1 (CCP1); GRAB_RAT; Fragmentin; Natural killer cell protease 1;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Granzyme B: 150-200/247
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
G1C9
理论分子量
25 kDa
浓度
1mg/ml
储存液
PBS, Glycerol, BSA.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
Granzyme B—是一种丝氨酸蛋白酶,作用在细胞凋亡中。
背景资料
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:50-200 | |
| IHC-F | Human | 1:50-200 | |
| IF | Human | 1:50-200 |
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
GZMB
蛋白名
Granzyme B
亚细胞定位
Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.
相似性
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain.
Contains 1 peptidase S1 domain.
功能
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
标记抗体
暂无标记数据
同靶标产品
暂无同靶标产品
相关文献
提示: 发表研究结果有使用 bsm-60779R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。
暂无相关文献
常见问题
暂无常见问题