滋养层细胞糖蛋白5T4重组兔单抗

bsm-52422R

重组兔单抗、mIHC精品抗体

5T4 Recombinant Rabbit mAb

滋养层细胞糖蛋白5T4重组兔单抗

TPBG_HUMAN; TPBG; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein (5T4 oncotrophoblast glycoprotein); M6P1; Wnt-activated inhibitory factor 1 (WAIF1); 5T4; TPBG_MOUSE; TPBG_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human TPBG/5T4

IgG

Liquid

affinity purified by Protein A

Recombinant

23B1

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

TPBG is a 420 amino acid single-pass type I membrane protein expressed by all types of trophoblasts as early as 9 weeks of development. TPBG contains an N-terminal putative signal sequence, a 310-residue extracellular region, a membrane anchorage domain and a 44-amino acid cytoplasmic tail with a potential phosphorylation site. The extracellular region has seven potential N-glycosylation sites and seven leucine-rich repeats, which are located in two regions separated by a hydrophilic stretch. Suggested to be involved in cell adhesion, TPBG may also be associated with tumor growth and progression.