5T4 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F | Bioss

bsm-52422R

重组兔单抗、mIHC精品抗体

5T4 Recombinant Rabbit mAb

滋养层细胞糖蛋白5T4重组兔单抗

TPBG_HUMAN; TPBG; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein (5T4 oncotrophoblast glycoprotein); M6P1; Wnt-activated inhibitory factor 1 (WAIF1); 5T4; TPBG_MOUSE; TPBG_RAT; trophoblast glycoprotein

Rabbit

KLH conjugated synthetic peptide derived from human TPBG/5T4

IgG

Liquid

affinity purified by Protein A

Recombinant

23B1

60-75 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

TPBG is a 420 amino acid single-pass type I membrane protein expressed by all types of trophoblasts as early as 9 weeks of development. TPBG contains an N-terminal putative signal sequence, a 310-residue extracellular region, a membrane anchorage domain and a 44-amino acid cytoplasmic tail with a potential phosphorylation site. The extracellular region has seven potential N-glycosylation sites and seven leucine-rich repeats, which are located in two regions separated by a hydrophilic stretch. Suggested to be involved in cell adhesion, TPBG may also be associated with tumor growth and progression.

Tpbg

Trophoblast glycoprotein

Membrane.

Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.