α横纹肌辅肌动蛋白重组兔单克隆抗体

bsm-52812R

重组兔单抗、mIHC精品抗体

Alpha Actinin 2 Recombinant Rabbit mAb

α横纹肌辅肌动蛋白重组兔单克隆抗体

CMD1AA; CMH23; CMYO8; CMYP8; MPD6; MYOCOZ; 1110008F24Rik; ACTN2_HUMAN; ACTN2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; ACTN2_MOUSE;

Rabbit

KLH conjugated synthetic peptide derived from human Sarcomeric Alpha Actinin

IgG

Liquid

affinity purified by Protein A

Recombinant

4C1

1mg/ml

PBS, Glycerol, BSA.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]