LOX Recombinant Rabbit mAb (一抗) - WB,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-60440R
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概述
产品编号
bsm-60440R
产品类型
重组兔单抗
英文名称
LOX Recombinant Rabbit mAb
中文名称
蛋白赖氨酸-6-氧化酶重组兔单抗
英文别名
LYOX_CHICK; LOX; Lysyl oxidase; 1.4.3.13; LYOX_HUMAN; LYOX_MOUSE; Ras excision protein; Rrg; LYOX_RAT; protein-lysine 6-oxidase
抗体来源
Rabbit
亚型
IgG/Kappa
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
A6E3
检测分子量
54 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cancer > Invasion/microenvironment > ECM > Extracellular matrix
Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment
Cardiovascular > Vasculature > Endothelium
Cardiovascular > Vasculature > Smooth muscle cell (SMC) > Extracellular matrix
Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Other Enzymes
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse | 1:500-1000 | |
| ICC/IF | Human | Mouse | 1:50-200 |
交叉反应
交叉反应: Human, Mouse
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靶标
基因名
LOX
蛋白名
Protein-lysine 6-oxidase
亚细胞定位
Secreted; extracellular space
组织特异性
Heart, placenta, skeletal muscle, kidney, lung and pancreas.
翻译后修饰
The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
Proteolytically activated by BMP1 (By similarity).
Proteolytically activated by BMP1 (By similarity).
相似性
Belongs to the lysyl oxidase family.
功能
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
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