phospho-Cofilin (Ser3) Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bs-3099R

磷酸化抗体、农牧业/家禽抗体

phospho-Cofilin (Ser3) Rabbit pAb

磷酸化丝切蛋白(Ser3)抗体

CFL1 | Cofilin (phospho-S3); p-Cofilin; phospho-Cofilin; p-CFL1; CFL1 | Cofilin (phospho-Ser3); CFL; HEL-S-15; cofilin; Cof; COF1_HUMAN; CFL1; 18 kDa phosphoprotein (p18); Cofilin, non-muscle isoform; COF1_MOUSE; COF1_RAT;

Rabbit

KLH conjugated Synthesised phosphopeptide derived from human Cofilin around the phosphorylation site of Ser3: A(p-S)GV

IgG

Liquid

affinity purified by Protein A

Polyclonal

18 kDa

18 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

丝切蛋白(cofilin)是细胞骨架塑形的重要调节因素,其主要功能是分解肌动蛋白微丝和增加肌动蛋白单体从肌动蛋白微丝的末端解离的速度,从而促进肌动蛋白微丝的循环,是目前为止已发现的肌动蛋白结合蛋白家族中唯一能够改变肌动蛋白微丝扭曲结构的蛋白。

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.