FITC标记的溶酶体相关膜蛋白2(CD107B)抗体

2026-01-04~2026-02-28,ZB1888
货号:bs-2379R-FITC
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概述

产品编号
bs-2379R-FITC
英文名称
LAMP2 Rabbit pAb, FITC conjugated
中文名称
FITC标记的溶酶体相关膜蛋白2(CD107B)抗体
英文别名
CD107 antigen-like family member B; CD107b; CD107b antigen; Igp110; Igp2; LAMP 2; LAMP 2C; LAMP B; LAMP-2; LAMP2_RAT; LAMPB; LGP110; Lysosomal associated membrane protein 2C; Lysosome associated membrane glycoprotein 2 precursor; Lysosome associated membrane protein 2; Lysosome-associated membrane glycoprotein 2; Lysosome-associated membrane protein 2; MAC3.
标记
FITC
Excitation spectrum: 495nm
Emission spectrum: 519nm
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human LAMP2: 301-411/411
亚型
IgG
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The protein encoded by the LAMP2 gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands and is thought to play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of the gene produces two known products, LAMP2a and LAMP2b. Isoform LAMP2a is highly expressed in placenta, lung and liver and has low expression in brain and skeletal muscle. The isoform detected by this antibody, LAMP2b, is highly expressed in skeletal muscle less so in brain, placental, lung, kidney and pancreas and has very low expression in liver.

产品应用

应用已检合格种属预测种属推荐稀释比例
IFHuman, Mouse, Rat1:100-500
Flow-CytHuman, Mouse, Rat1ug/test
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
LAMP2
蛋白名
Lysosome-associated membrane glycoprotein 2
亚细胞定位
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
翻译后修饰
O- and N-glycosylated; some of the N-glycans attached to Lamp-2 are polylactosaminoglycans.
相似性
Belongs to the LAMP family.
功能
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

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