CH25H Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bs-6480R

CH25H Rabbit pAb

胆固醇25羟化酶抗体

C25H; m25OH; CH25H_HUMAN; CH25H; Cholesterol 25-monooxygenase (h25OH); 1.14.99.38; CH25H_MOUSE; Cholesterol 25-monooxygenase (m25OH); CH25H_RAT; Cholesterol 25-monooxygenase; cholesterol 25-hydroxylase

Rabbit

KLH conjugated synthetic peptide derived from human CH25H: 1-100/272

IgG

Liquid

affinity purified by Protein A

Polyclonal

32 kDa

11 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.