ACADM Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-60484R
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常见问题
概述
产品编号
bsm-60484R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
ACADM Recombinant Rabbit mAb
中文名称
酰基辅酶A脱氢酶中链重组兔单抗
英文别名
ACAD1; MCAD; MCADH; ACADM_HUMAN; ACADM; Medium chain acyl-CoA dehydrogenase (MCADH); 1.3.8.7; acyl-CoA dehydrogenase medium chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; medium-chain acyl-CoA dehydrogenase
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human ACADM: 150-200/421
亚型
IgG/Kappa
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
H5A10
检测分子量
45 kDa
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers
Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation
Metabolism > Types of disease > Cancer
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
酰基辅酶，是一种特殊的酰基链长度为4-16的脱氢酶，它催化脂肪酸β氧化的起始步骤。利用电子转移黄蛋白（ETF）作为电子受体，通过ETF-泛醌氧化还原酶（ETF脱氢酶）将电子转移到线粒体呼吸链。
背景资料
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human, Mouse, Rat | 1:50-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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暂无相关产品
靶标
基因名
ACADM
蛋白名
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
亚基
Homotetramer. Interacts with the heterodimeric electron transfer flavoprotein ETF.
亚细胞定位
Mitochondrion matrix.
疾病
Acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]: An inborn error of mitochondrial fatty acid beta-oxidation which causes fasting hypoglycemia, hepatic dysfunction and encephalopathy, often resulting in death in infancy. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似性
Belongs to the acyl-CoA dehydrogenase family.
功能
This enzyme is specific for acyl chain lengths of 4 to 16.
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