SMYD2 Recombinant Mouse mAb (一抗) | Bioss
货号：bsm-60487M
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bsm-60487M
产品类型
重组小鼠单抗
英文名称
SMYD2 Recombinant Mouse mAb
中文名称
组蛋白甲基转移酶SMYD2重组小鼠单抗
英文别名
HSKM-B; KMT3C; ZMYND14; 1110020E07Rik; 4930402C15; SMYD2_BOVIN; SMYD2; Histone methyltransferase SMYD2; SET and MYND domain-containing protein 2; 2.1.1.-; SMYD2_HUMAN; Lysine N-methyltransferase 3C; SMYD2_MOUSE; SMYD2_PIG; SMYD2_RAT;
抗体来源
Mouse
亚型
IgG1, Kappa
性状
Liquid
纯化方法
affinity purified by Protein G
克隆类型
Recombinant
克隆号
B10D2
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Rat | 1:500-1000 | |
| ICC/IF | Human | Rat | 1:100-500 |
交叉反应
交叉反应: Human (predicted: Rat)
相关产品
暂无相关产品
靶标
基因名
SMYD2
蛋白名
N-lysine methyltransferase SMYD2
亚基
Interacts with RNA polymerase II and HELZ. Interacts with SIN3A and HDAC1 (By similarity). Interacts (via MYND-type zinc finger) with EPB41L3. Interacts (via SET domain) with p53/TP53. Interacts with RB1 and HSP90AA1.
亚细胞定位
Cytoplasm; cytosol. Nucleus.
相似性
Contains 1 MYND-type zinc finger.
Contains 1 SET domain.
Contains 1 SET domain.
功能
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
同靶标产品
相关文献
提示: 发表研究结果有使用 bsm-60487M 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。