MAML3 Rabbit pAb (一抗) | Bioss
货号：bs-12398R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bs-12398R
产品类型
农牧业/家禽抗体
英文名称
MAML3 Rabbit pAb
中文名称
主导控制样蛋白3抗体
英文别名
CAGH3; ERDA3; GDN; MAM-2; MAM2; TNRC3; mam-3; MAML3_HUMAN; MAML3; KIAA1816;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human MAML3: 931-1030/1134
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
122 kDa
检测分子量
110 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Pig, Sheep, Cow, Horse | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Pig, Sheep, Cow, Horse)
相关产品
暂无相关产品
靶标
基因名
MAML3
蛋白名
Mastermind-like protein 3
亚基
Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
亚细胞定位
Nucleus; nuclear speckle. Note=Nuclear, in a punctate manner
相似性
Belongs to the mastermind family.
功能
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.
同靶标产品
相关文献
提示: 发表研究结果有使用 bs-12398R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。