CDH17／LI-cadherin Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Name: 肝肠钙粘连蛋白重组兔单抗（CDH17／LI-cadherin Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-60434R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-60434R

产品详情

概述

产品编号

bsm-60434R

产品类型

重组兔单抗、mIHC精品抗体

英文名称

CDH17／LI-cadherin Recombinant Rabbit mAb

中文名称

肝肠钙粘连蛋白重组兔单抗

英文别名

CDH16; HPT-1; HPT1; CAD17_HUMAN; CDH17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin (LI-cadherin); cadherin 17; cadherin 17, LI cadherin (liver-intestine)

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human Cadherin 17: 1-65/832

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

B5A7

理论分子量

90 kDa

检测分子量

120 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

研究领域

Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 1015 Human

Omim : 603017 Human

SwissProt : Q12864 Human

Unigene : 591853 Human

产品介绍

Cadherin家族，即钙离子依赖的细胞粘附素家族，是Takeichi最早发现的一种介导细胞间相互聚集的粘附分子，对生长发育过程中细胞的选择性聚集具有至关重要的作用。

背景资料

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

基因名

CDH17

蛋白名

Cadherin-17

亚细胞定位

Cell membrane; Single-pass type I membrane protein (Potential).

组织特异性

Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. Similarity : Contains 7 cadherin domains.

相似性

Contains 7 cadherin domains.

功能

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.