真核肽链释放因子3a/eRF3重组兔单抗

bsm-60585R

重组兔单抗

eRF3/GSPT1 Recombinant Rabbit mAb

真核肽链释放因子3a/eRF3重组兔单抗

551G9.2; ETF3A; GST1; eRF3a; ERF3A_HUMAN; GSPT1; Eukaryotic peptide chain release factor subunit 3a; G1 to S phase transition protein 1 homolog; 3.6.5.-;

Rabbit

KLH conjugated synthetic peptide derived from human eRF3/GSPT1

IgG

Liquid

affinity purified by Protein A

Recombinant

H5G9

56 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.