MAP4 Rabbit pAb (一抗) | Bioss
货号：bs-4128R
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概述
产品编号
bs-4128R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
MAP4 Rabbit pAb
中文名称
微管相关蛋白4抗体
英文别名
MAP-4; Mtap-4; Mtap4; MAP4_HUMAN; MAP4; MAP4_MOUSE; MAP4_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human MAP4: 701-800/1152
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
121 kDa
检测分子量
121 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse | Rat, Pig, Cow, Dog, Horse | 1:500-2000 |
交叉反应
交叉反应: Human, Mouse (predicted: Rat, Pig, Cow, Dog, Horse)
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靶标
基因名
MAP4
蛋白名
Microtubule-associated protein 4
亚基
Interacts with SEPT2; this interaction impedes tubulin-binding (By similarity).
亚细胞定位
Cytoplasm, cytoskeleton.
组织特异性
Testis, striated and cardiac muscle.
翻译后修饰
Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-760 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 4 is phosphorylated on Ser-333 and Ser-334 (By similarity).
相似性
Contains 4 Tau/MAP repeats.
功能
Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
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