phospho-Cdc25B (Ser353) Rabbit pAb (一抗) | Bioss

bs-5245R

磷酸化抗体

phospho-Cdc25B (Ser353) Rabbit pAb

磷酸化细胞分裂周期蛋白25B抗体

Cdc25B (phospho-S353); p-Cdc25B; phospho-Cdc25B; Cdc25B (phospho-Ser353); MPIP2; MPIP2_HUMAN; CDC25B; Dual specificity phosphatase Cdc25B; 3.1.3.48; CDC25HU2; MPIP2_MOUSE; Cdc25m2; MPIP2_RAT;

Rabbit

KLH conjugated Synthesised phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser353: RR(p-S)VT

IgG

Liquid

affinity purified by Protein A

Polyclonal

65 kDa

65 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].