组织因子(CD142)兔单克隆抗体

Rrmab?兔单抗
2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
组织因子(CD142)兔单克隆抗体
货号:bsm-52647R
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概述

产品编号
bsm-52647R
产品类型
重组兔单抗
英文名称
Tissue factor Recombinant Rabbit mAb
中文名称
组织因子(CD142)兔单克隆抗体
英文别名
TF_HUMAN; F3; TF; Coagulation factor III; Thromboplastin; TF_MOUSE; Cf-3; Cf3; TF_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Tissue factor: 1-100/295
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
6A4
理论分子量
35 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
组织因子(CD142)兔单克隆抗体

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:100-500
IHC-FHuman, Mouse, Rat1:100-500
IFHuman, Mouse, Rat1:100-500
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
F3
蛋白名
Tissue factor
亚基
Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.
亚细胞定位
Isoform 1: Membrane; Single-pass type I membrane protein.
Isoform 2: Secreted.
组织特异性
Lung, placenta and pancreas.
相似性
Belongs to the tissue factor family.
功能
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

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