前梯度同源蛋白2重组兔单抗

bsm-52594R

重组兔单抗、mIHC精品抗体

AGR2 Recombinant Rabbit mAb

前梯度同源蛋白2重组兔单抗

AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; RIFTD; XAG-2; Agr2h; mAG-2; AGR2_HUMAN; AGR2; Secreted cement gland protein XAG-2 homolog; AGR2_MOUSE; Protein Gob-4; Gob4;

Rabbit

A synthesized peptide derived from human AGR2: 1-64

IgG

Liquid

affinity purified by Protein A

Recombinant

3F8

20 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

AGR2 is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and ?dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.