着丝粒蛋白C1重组兔单抗
Rrmab®兔单抗
货号：bsm-54360R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bsm-54360R
产品类型
重组兔单抗
英文名称
CENPC1 Recombinant Rabbit mAb
中文名称
着丝粒蛋白C1重组兔单抗
英文别名
CENP-C; CENPC1; MIF2; hcp-4; CENPC_HUMAN; CENPC; Centromere autoantigen C; Centromere protein C 1 (CENP-C 1); Interphase centromere complex protein 7; ICEN7;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CENPC: 400-530
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3A7
理论分子量
107 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse | 1:500-2000 | |
| ICC/IF | Human | Mouse | 1:50-200 |
交叉反应
交叉反应: Human, Mouse
相关产品
暂无相关产品
靶标
基因名
CENPC
蛋白名
Centromere protein C
亚基
Oligomer. Component of the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU. The CENPA-NAC complex interacts with the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. Binds to DAXX. Interacts directly with CENPA.
亚细胞定位
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres.
相似性
Belongs to the CENPC family.
功能
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
标记抗体
暂无标记数据
同靶标产品
暂无同靶标产品
相关文献
提示: 发表研究结果有使用 bsm-54360R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。
暂无相关文献
常见问题
暂无常见问题