GABRR1 Rabbit pAb (一抗) | Bioss
货号：bs-12084R
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概述
产品编号
bs-12084R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
GABRR1 Rabbit pAb
中文名称
G氨基丁酸A型受体rho1/GABAA Rρ1抗体
英文别名
GBRR1_HUMAN; GABRR1; GABA(A) receptor subunit rho-1 (GABAAR subunit rho-1); GABA(C) receptor;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human GABRR1: 201-300/479 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
53 kDa
检测分子量
53 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | Rabbit, Pig, Cow, Dog | 1:500-2000 |
交叉反应
交叉反应: Human, Mouse, Rat (predicted: Rabbit, Pig, Cow, Dog)
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靶标
基因名
GABRR1
蛋白名
gamma-aminobutyric acid receptor subunit rho-1
亚基
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1
亚细胞定位
Cell junction, synapse, postsynaptic cell membrane; Multipass membrane protein. Cell membrane; Multipass membrane protein.
组织特异性
Highly expressed in the retina and in a lesser extent in brain, lung and thymus.
相似性
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily.
功能
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand gated chloride channels. GABRR1 is a member of the rho subunit family
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