FCER2_HUMAN; FCER2; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; CD23A; CLEC4J; FCE2; IGEBF; FCER2_MOUSE; Fcer2a; Fc epsilon receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23A); Fc fragment of IgE, low affinity II, receptor for (CD23); Fc fragment of IgE receptor II; Fc epsilon RII
抗体来源
Mouse
亚型
Mouse IgG1, k
性状
Liquid
纯化方法
affinity purified by Protein G
克隆类型
Monoclonal
克隆号
2F10
理论分子量
36 kDa
检测分子量
45 kDa
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human
1:100-500
IHC-F
Human
1:100-500
IF
Human
1:100-500
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
FCER2
蛋白名
Low affinity immunoglobulin epsilon Fc receptor
亚细胞定位
Cell membrane; Single-pass type II membrane protein. Secreted. Note=Also exists as a soluble excreted form.
翻译后修饰
N- and O-glycosylated.
相似性
Contains 1 C-type lectin domain.
功能
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).