DSS1 Rabbit pAb (一抗) | Bioss
货号：bs-14432R
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概述
产品编号
bs-14432R
产品类型
农牧业/家禽抗体
英文名称
DSS1 Rabbit pAb
中文名称
先天性裂手/裂足畸形相关蛋白DSS1抗体
英文别名
C7orf76; DSS1; ECD; PSMD15; SHFD1; SHFM1; SHSF1; Shfdg1; SEML_HUMAN; SEM1; SEM1 26S proteasome subunit; split hand/foot malformation (ectrodactyly) type 1; chromosome 7 open reading frame 76; SEM1, 26S proteasome complex subunit; deleted in split-hand/foot 1
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human DSS1: 1-70/70
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
8.3 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
SEM1 (SEM1, 26S Proteasome Complex Subunit) is a Protein Coding gene. Diseases associated with SEM1 include Split Foot and Split Hand-Split Foot Malformation. Among its related pathways are RET signaling and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Human | Rabbit, Pig, Cow | 1:100-500 |
| IHC-F | Human | Rabbit, Pig, Cow | 1:100-500 |
| IF | Human | Rabbit, Pig, Cow | 1:100-500 |
交叉反应
交叉反应: Human (predicted: Rabbit, Pig, Cow)
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靶标
基因名
SEM1
蛋白名
Putative protein SEM1, isoform 2
亚基
Part of the 26S proteasome. Interacts with the C-terminal of BRCA2.
组织特异性
Expressed in limb bud, craniofacial primordial and skin.
相似性
Belongs to the DSS1/SEM1 family.
功能
The gene for DSS1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. DSS1 has been proposed to be a candidate for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
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