Factor IX Rabbit pAb (一抗) | Bioss

bs-9500R

农牧业/家禽抗体

Factor IX Rabbit pAb

凝血因子9抗体

F9 p22; FIX; HEMB; P19; PTC; THPH8; FA9_HUMAN; F9; Christmas factor; Plasma thromboplastin component (PTC); 3.4.21.22; coagulation factor IX; Factor IX; plasma thromboplastic component; Christmas disease; hemophilia B

Rabbit

KLH conjugated synthetic peptide derived from human Coagulation factor IXa heavy chain: 381-461/461

IgG

Liquid

affinity purified by Protein A

Polyclonal

26/47 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3). Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4). Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5). Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6).