PE标记的细胞粘附分子CD112抗体

bs-2679R-PE

CD112 Rabbit pAb, PE conjugated

PE标记的细胞粘附分子CD112抗体

Nectin-2; Nectin2; Nectin 2; CD 112; CD112 antigen; Herpes virus entry mediator B; Herpes virus entry protein B; Herpesvirus entry mediator B; Herpesvirus entry protein B; Hve B; HveB; Poliovirus receptor like 2; Poliovirus receptor related 2(herpesvirus entry mediator B); Poliovirus receptor related 2; Poliovirus receptor related protein 2; Poliovirus receptor-related protein 2; Nectin cell adhesion molecule 2; HVEB; PRR 2; PRR2; PVRL 2; PVRL2; NECT2_HUMAN; PVRR 2; PVRR2.

PE
Excitation spectrum: 496/564nm
Emission spectrum: 578nm

Rabbit

KLH conjugated synthetic peptide derived from human CD112: 251-350/538 <Extracellular>

IgG

affinity purified by Protein A

Polyclonal

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

细胞粘附分子Nectin-2（CD112）是一种同源性非钙依赖型的CAM，属免疫球蛋白超家族，由nectin-1、nectin-2、nectin-3组成，广泛存在于肿瘤、正常细胞，神经细胞、内皮细胞等，CD112也是单纯疱疹病毒(HSV-1和HSV-2)的受体，具有同型或异型细胞粘附活性.在多发性硬化中呈现高表达。

Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.