CD27重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
CD27重组兔单抗
货号:bsm-54318R
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概述

产品编号
bsm-54318R
产品类型
重组兔单抗
英文名称
CD27 Recombinant Rabbit mAb
中文名称
CD27重组兔单抗
英文别名
CD27_HUMAN; CD27; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; TNFRSF7; CD27_MOUSE;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CD27: 60-90
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3C3
理论分子量
55 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
CD27重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman1:500-2000
Flow-CytHuman1:50-100
ICC/IFHuman1:50-200

交叉反应

交叉反应: Human

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靶标

基因名
CD27
蛋白名
CD27 antigen
亚基
Homodimer. Interacts with SIVA1 and TRAF2.
亚细胞定位
Membrane; Single-pass type I membrane protein.
组织特异性
Found in most T-lymphocytes.
翻译后修饰
Phosphorylated.
O-glycosylated with core 1 or possibly core 8 glycans.
相似性
Contains 3 TNFR-Cys repeats.
功能
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

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