Clathrin heavy chain Rabbit pAb (一抗) - WB,ICC/IF | Bioss
货号：bs-2932R
产品详情
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概述
产品编号
bs-2932R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
Clathrin heavy chain Rabbit pAb
中文名称
网格蛋白重链抗体
英文别名
CHC; CHC17; CLH-17; CLTCL2; Hc; MRD56; 3110065L21Rik; CLH1_HUMAN; CLTC; Clathrin heavy chain on chromosome 17 (CLH-17); CLH17; KIAA0034; CLH1_MOUSE; CLH1_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Clathrin heavy chain.: 401-500/1675
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
192 kDa
检测分子量
185 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008].
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Rabbit, Pig, Cow, Dog, Bee, Ant, Frog, Silkworm | 1:500-2000 |
| ICC/IF | Human | Mouse, Rat, Rabbit, Pig, Cow, Dog, Bee, Ant, Frog, Silkworm | 1:50-200 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Cow, Dog, Bee, Ant, Frog, Silkworm)
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靶标
基因名
CLTC
蛋白名
Clathrin heavy chain 1
亚基
Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1. Interacts with DENND1A, DENND1B and DENND1C (By similarity). May interact with OCRL. Interacts with ERBB2 (By similarity).
亚细胞定位
Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
相似性
Belongs to the clathrin heavy chain family.
Contains 7 CHCR (clathrin heavy-chain) repeats.
Contains 7 CHCR (clathrin heavy-chain) repeats.
功能
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
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