NMUR1 Rabbit pAb (一抗) - WB | Bioss

bs-11420R

NMUR1 Rabbit pAb

G蛋白偶联受体66/神经调节肽U受体1抗体

(FM-3); FM-3; FM3; GPC-R; GPR66; NMU1R; NMUR1_HUMAN; NMUR1; NMU-R1; G-protein coupled receptor 66; G-protein coupled receptor FM-3;

Rabbit

KLH conjugated synthetic peptide derived from human NMUR1: 31-80/426 <Extracellular>

IgG

Liquid

affinity purified by Protein A

Polyclonal

47 kDa

47 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.