NUSAP1 Rabbit pAb (一抗) | Bioss
货号：bs-7764R
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概述
产品编号
bs-7764R
产品类型
农牧业/家禽抗体
英文名称
NUSAP1 Rabbit pAb
中文名称
核仁和纺锤体相关蛋白1抗体
英文别名
ANKT; BM037; LNP; NUSAP; PRO0310p1; Q0310; SAPL; nucleolar and spindle associated protein 1
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human NUSAP1: 151-250/441
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
49 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
NUSAP1 is a microtubule-associated protein with the capacity to bundle and stabilize microtubules. It may associate with chromosomes and promote the organization of mitotic spindle microtubules around them. There are five different isoforms.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Mouse, Rat | Human, Rabbit, Pig, Chicken | 1:100-500 |
| IHC-F | Mouse, Rat | Human, Rabbit, Pig, Chicken | 1:100-500 |
| IF | Mouse, Rat | Human, Rabbit, Pig, Chicken | 1:100-500 |
交叉反应
交叉反应: Mouse, Rat (predicted: Human, Rabbit, Pig, Chicken)
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靶标
基因名
NUSAP1
蛋白名
Nucleolar and spindle-associated protein 1
亚基
Interacts with DNA and microtubules. Microtubule bundling is inhibited by IPO7, KPNA2 and KPNB1 while association with DNA is also inhibited by IPO7 and KPNA2.
亚细胞定位
Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Chromosome.
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR.
Ubiquitinated. Ubiquitination by FZR1 may lead to proteasome-dependent degradation of this protein.
Ubiquitinated. Ubiquitination by FZR1 may lead to proteasome-dependent degradation of this protein.
功能
Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.
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