CHD4 Rabbit pAb (一抗) | Bioss
货号：bs-13893R
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概述
产品编号
bs-13893R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
CHD4 Rabbit pAb
中文名称
染色质解旋酶DNA结合蛋白Mi2β抗体
英文别名
CHD-4; Mi-2b; Mi2-BETA; SIHIWES; 9530019N15Rik; D6Ertd380e; Mi-2beta; mKIAA4075; CHD4_HUMAN; CHD4; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; 3.6.4.-; CHD4_MOUSE; chromodomain helicase DNA binding protein 4
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CHD4: 21-120/1912
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
218 kDa
检测分子量
280 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Rabbit, Pig, Cow, Dog, Horse | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Rabbit, Pig, Cow, Dog, Horse)
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靶标
基因名
CHD4
蛋白名
Chromodomain-helicase-DNA-binding protein 4
亚细胞定位
Nucleus. Cytoplasm > cytoskeleton > centrosome. Associates with centrosomes in interphase.
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR.
相似性
Belongs to the SNF2/RAD54 helicase family.
Contains 2 chromo domains.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 2 PHD-type zinc fingers.
Contains 2 chromo domains.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 2 PHD-type zinc fingers.
功能
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
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